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In Poland, with limited reimbursement of new antihyperglycaemic agents, the most readily available and affordable classes of agents are sulfonylurea derivatives, PPAR- agonists, and acarbose [125, 256, 257]

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found that 25(OH) D deficiency is a critical risk factor for minor amputations in patients with diabetic foot ulcers (77)

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[2] [5] Other important safety considerations include risk of diabetic retinopathy complications, gallbladder disease, and acute kidney injury

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