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Glucagon acting at the GLP-1 receptor contributes to -cell regeneration induced by glucagon receptor antagonism in diabetic mice

Science 376 , 410416 (2022)

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While GLP-1s are shaking up the health and wellness industry in a big way, studies show the hefty price tag for semaglutide can be a real deterrent for those who need it most

Determination of the IC 50 values for these compounds in CHO K1 cells expressing human TRPV1 revealed that exendin 939 had the lowest IC 50 value for inhibiting CAP-induced TRPV1 activation