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Description

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TMAO activates macrophage cell surface receptor Toll-like receptor 4 (TLR4) [142], which activates MyD88-dependent signaling and further stimulates NF-B [143] (Figure 4)

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MYC, myelocytomatosis oncogene

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Although the full mechanism underlying this difference remains unclear, several contributing factors have been proposed

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Raucci R, Rusolo F, Sharma A, Colonna G, Castello G, Costantini S (2013) Functional and structural features of adipokine family

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