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In addition, they participated in the regulation of the expression of Bax, Bcl2, caspase-3, and cytochrome, which are highly related to apoptosis, as well as promoting a positive regulation of p53, a key molecule involved in cell death (91)

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A third recurring strand is bidirectional nitric oxide system rebalancing - BPC-157 counteracts both L-NAME-induced NOS blockade and L-arginine substrate overload in rat models