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- Retatrutide is studied as a multi-receptor peptide in controlled research environments where investigators are evaluating the interaction between GLP-1 receptor signaling, GIP receptor activity, glucagon receptor pathways, metabolic adaptation, insulinotropic pathway behavior, appetite-associated signaling models, and energy expenditure biology

Guyatt G, Zhao Y, Mayer M, Briel M, Mustafa R, Izcovich A, et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Argano C., Colomba D., Di Chiara T., La Rocca E