Phase 2 data showed 24.2% mean body weight reduction at the 12 mg dose over 48 weeks
No dual or single agonist compound gives researchers access to the GCGR pathway
However, they also say that a decent amount of muscle loss is par for the course for anyone losing weight rapidly, specifically highlighting those who have had bariatric surgery, and not necessarily specific to GLP-1s
Injection site selection plays a crucial rolethe abdomen (at least 2 inches from the navel), thigh, and upper arm are FDA-approved sites for most GLP-1 medications, with comfort levels varying between individuals
Emerging Research on Alcohol Use Disorder Several recent studies have examined whether GLP-1 receptor agonists reduce alcohol cravings and consumption in people with alcohol use disorder
And if you're struggling with sleep, I did a two part episode series on how to get better sleep