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Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes (Phase 2 trial)

However, efficacy in these latter indications remains under investigation

GLP-1 and GLP-1 RA (such as Exenatide and Liraglutide) were shown to have an anti-inflammatory action by reducing monocyte adhesion and macrophage accumulation, thus stabilizing atherosclerotic plaque, and slowing atherosclerosis in animal models [47,48,49]

It is not licensed by the MHRA in the UK for any indication, and evidence supporting its use in the general population for weight management or body composition purposes is limited

This is not usually captured in scientific awards, such as the Nobel Prize, which tend to be selective in who gets honoured

Throughout the duration of my 90-day trial, I was pleasantly surprised