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Moser KL, Kelly JA, Lessard CJ, Harley JB (2009) Recent insights into the genetic basis of systemic lupus erythematosus

Figure 1 Furthermore, SAM serves as a methyl donor, methylating DNA and proteins, including histones (Zade et al., 2023), which in turn influences epigenetic regulation, and gene expression ( Figure 1 )

Due to the rapid proliferation and metabolism of tumor cells, glycolysis is highly active, and the tumor microenvironment (TME) often exhibits characteristics of hypoxia and glucose deprivation

51 Similarly, Behrendt et al

Therefore, there is an urgent need for medications aimed at preventing and intervening in the progression of goiter

Future directions include the design and synthesis of novel compounds that can mitigate these side effects while maintaining or enhancing efficacy