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Additionally, certain nanocarriers still face payload limitations- while NLCs improved capacity over solid lipid nanoparticles, some highly bioactive nutraceuticals require even higher loading or multiple compound co-entrapment, pushing existing techniques to their limits (189193)

Given the rising use of GLP-1 RAs, including off-label use in non-diabetic populations for weight reduction, clinicians should be aware of its potential pancreatic effects

Epilepsy can be viewed as a metabolic disease, and primordial mechanisms evoked by compounds such as adenosine could be highly relevant to seizures and epileptogenesis