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Muscle is also your best blood sugar regulator

J Biol Chem 248:34263432 Marx W, Teleni L, Opie R, Kelly J, Marshall S, Itsiopoulos C, Isenring E (2017) Efficacy and effectiveness of carnitine supplementation for cancer-related fatigue: a systematic literature review and meta-analysis

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Obesity is associated with lower testosterone levels

If your cells are absorbing sugar rapidly because of berberine, and your liver is producing less sugar because of the medication, your blood glucose levels could drop below a healthy range