PHD activates the pseudohypoxic response by stabilizing HIF-1, which is a well-known tumorigenesis enhancer, and as a transcription factor, maintains the metabolic reprogramming of cancer cells to support their survival 127
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Neutralising free radicals, it minimises swelling caused by environmental stressors (were talking, UV rays, weather, pollution) and by supporting skin hydration, helps maintain skin thats less prone to puffiness