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Mice bearing IMR5 xenografts with a mean diameter of 5 mm were treated with 3 mg/kg DPI (P.O., 5 days/week), 30 mg/kg MitoQ (P.O., 3 days/week), or their combination (1.5 mg/kg DPI (P.O., 5 days/week) and 20 mg/kg MitoQ (P.O., 3 days/week))

References Van der Lely AJ, Lamberts SW, Jauch KW, et al

Role of lipid peroxidation and PPAR- in amplifying glucose-stimulated insulin secretion

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PMID: 33 ZanganehSHutterGSpitlerRLenkovOMahmoudiMShawAet al