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Hypoxia-inducible factor as an angiogenic master switch

NPJ Aging 10 , 7 (2024)

ACE states: Exercises that involve more muscle tissue require more oxygen, which helps the body increase its net energy expenditure. These movements can also elevate heart rate and provide a cardiovascular training benefit while building strength. Examples discussed by ACE include squats, lunges, presses, and rowing movements

It also avoids the pain and cost of repeated clinic visits

The beneficial effect of TZT in T2DM and obesity is related to the direct activation of GIP and GLP-1 receptors with subsequent improvement of insulin sensitivity and reduction of bodyweight

This work was supported by National Natural Science Foundation of China (8246070319)