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Rybelsus makes sense in a fairly narrow set of circumstances: You have type 2 diabetes, and blood sugar control is your primary goal, while weight loss is secondary Your commercial insurance covers Rybelsus for diabetes and the cost with the savings card is significantly lower than Wegovy Youve already been stable on Rybelsus for diabetes and dont want to switch medications A triple board-certified physician in obesity medicine noted that although Rybelsus has the same active ingredient as Ozempic, it wouldnt typically be used off-label for weight loss, because there are other weight-loss medications that work better

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