While this finding is of great interest to the field of konzo as well as other neurodegenerative diseases, we cannot determine if the reduction in GPx3 is a result of disease or an inherent contributing factor for disease that is triggered by a micronutrient deficiency or underlying genetic variability
Post-mortem analysis of the prefrontal cortex showed significantly increased levels of 8-OH-Gua (see also above) which may in turn affect the aggregation of proteins (Balmus et al
The primary outcome of interest was the incidence of dementia, Alzheimers disease, vascular dementia, frontotemporal dementia, Parkinsons disease, extrapyramidal and movement disorders, and dementia with Lewy bodies
This blood work can help understand the body's ability to heal, and what deficiencies need to be addressed
In these cases, the brains reward recalibration enhances focus and motivation rather than dulling it
So keep in mind there's no one supplement, no one diet, no one surgery, no one medication that is going to completely treat endometriosis because endometriosis is affecting the immune system, the gut [00:23:00] blood sugar regulation, uh, pain signaling and hormones and, um, your nervous system like and all at the same time