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Why GLP-1 Agonists Outperform Metformin for Weight Loss Metformin was developed as a diabetes medication, not a weight loss drug, so its metabolic effects are indirect and modest

prioritize 78 hours nightly Stress management improves peptide efficacy Choosing the Right Peptide Tesamorelin vs Ipamorelin Tesamorelin Best for visceral fat reduction Requires lab monitoring and daily injections Ipamorelin Safer, slower, long-term body recomposition Minimal monitoring required Combining Peptides for Maximum Effect Some practitioners combine tesamorelin, ipamorelin, and sermorelin to: Stimulate GH via multiple pathways Achieve more balanced fat loss and muscle preservation Important Only under medical supervision Dose and timing require careful adjustment Key Takeaways Tesamorelin = fast, targeted visceral fat reduction Ipamorelin = safe, steady fat loss with muscle preservation Both peptides enhance GH naturally, but lifestyle factors remain crucial Medical supervision is essential References Bartke, A

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