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Interesting that it removes fasting and injections, that could really boost adherence

In rabbits, but not in rats, there was a statistically non-significantly higher number of post-implantation losses at the highest dose tested (600 mg/kg per day) compared to the control group

This is why stopping it suddenly can cause withdrawal symptoms

Wei CJ, Augusto E, Gomes CA, Singer P, Wang Y, Boison D, et al

Facial changes are usually due to weight loss, especially when weight drops quickly

Researchers analyzing body composition data have noted not only greater overall weight reduction but also a favorable ratio of fat loss to lean mass preservation, consistent with the hypothesized energy-expenditure component