4.4 Clinical trials: reproductive and metabolic outcomes of MI in PCOS Across randomized trials and meta-analyses, MI consistently signals benefit for reproductive endpoints in PCOS, though the magnitude varies with phenotype, baseline IR, and treatment context (143, 148)
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The medication improves insulin sensitivity, reduces cardiovascular risks, preserves kidney function, improves gut function, and has neuroprotective and anti-inflammatory effects
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As such, tirzepatide is anticipated to receive marketing approval by mid-to-late 2022