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In particular, a subset of inflammatory immune cells called Th17 cells are principally responsible for driving inflammation in Crohns disease, while Th2 cells drive inflammation in ulcerative colitis

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In Vitro Skin Irritation Test HaCaT keratinocytes were cultured in DMEM containing 10% fetal bovine serum and 1% penicillin/streptomycin and were maintained under 37 C with humidified 5% CO 2

Clinical observations and research protocols suggest a graduated approach to dosing, beginning with lower doses to assess individual tolerance and response before progressing to higher doses if needed

B Wu & D Dong (2012) Human cytosolic glutathione transferases: structure, function, and drug discovery