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a trend which continued, resulting in a close to twenty-fold increase 17.9% in incident semaglutide patients between 2019 and 2023

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To minimize side effects (lung toxicity, ototoxicity, nephrotoxicity) some pediatric protocols used reduced dose of bleomycin from once per week to once per cycle (PEb) [322,323,324] or carboplatin instead of cisplatin [325, 326]