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The safety profile for long-term use remains unclear, and some countries have not approved it for cosmetic distribution

A study by Cao et al

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Tirzepatide is a novel, once-weekly injectable peptide-based medication that combines the actions of two hormones: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1)

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Mechanistic studies in animal models suggest that mucosal targeting is likely to offer better protection against respiratory infections [43], but methods for inducing mucosal immunity are in the earliest stages of testing