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In addition to dual agonists, triple agonists hold enhanced therapeutic potential for obesity and type 2 diabetes (Table 1)

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doi: 10.1038/s41467-019-11107-x 17 Cancer Genome Atlas N

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Concurrent treatment with curcumin (5, 30, 60 mg/kg, p.o.) for 19 days resulted in a significant decrease in immobility time, hyperalgesia, oxidative stress (brain lipid peroxidation, GSH levels and nitrite levels,) and TNF- levels, in a dose dependent manner