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The most commonly prescribed GLP-1 agonist is semaglutide, which has gained popularity in recent years after the Food and Drug Administration (FDA) approved it for the treatment of diabetes in 2017 (under the brand name Ozempic), for the treatment of obesity in 2021 (under the brand name Wegovy), and for reducing cardiovascular disease risk in 2024 (Wegovy)

In animal studies SGLT2 inhibitors were excreted in breast milk and affected neonatal growth, but human data are not available

public comment period through June 2026)

Safety concerns frequently stem from misunderstandings about dosing, medication sourcing, and individual health differences that affect how bodies respond to GLP-1 therapy

Here is what the research and real-world experience show