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That said, it is not FDA-approved, so it should only be considered under licensed medical supervision

To place CJC-1295 against an entirely different substance class, the comparison Retatrutide vs

It is unclear to what extent the reduction in lean mass is attributable to loss of skeletal muscle mass per se, which comprises only one component of total body lean mass in mice, but the lack of effect on fat mass is consistent with the reported paucity of IGF-1Rs on mature adipocytes

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If retatrutide reduces major cardiovascular events (like semaglutide did in SELECT), the heart rate increase will be viewed as a pharmacologically interesting but clinically irrelevant side effect