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Such uncertainty can blur the statistical picture and generate spurious associations

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I just faced a similar, although not identical, situation, made the opposite decision, and I can absolutely see why Mike went the other direction

For example, a much smaller patient will need a lower dose, whereas someone with greater body mass or a resistance to the medication will likely need a higher one

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Lyophilization removes water under controlled freezing and drying conditions, producing a dry cake that is often easier to store and ship than solution material