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Reactive proteinmediated low densitylipoprotein uptake by macrophages

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Orforglipron tucks into a compact pocket in the upper helical bundle, contacting transmembrane helices 1, 2, 3, and 7 plus a key extracellular residue, and not engaging helices 4, 5, and 6 the way the peptide does

Human prostate cancer tissue expresses large amounts of GLP-1 receptors [59]

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