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Nishimaru K, Tanaka Y, Tanaka H, Shigenobu K (2000) Positive and negative inotropic effects of muscarinic receptor stimulation in mouse left atria

The conformation change in the receptor activates G proteins, a heterotrimeric protein with , , and subunits

Although scientists do not yet fully understand the mechanisms underlying these wide-ranging actions, a clearer picture is beginning to emerge

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