NAC, which boosts glutathione in the body, restored the ability of immune cells to kill the bacteria that cause tuberculosis [36]
However, in the DSS+40 mg/kg ATT-I + AAV-shCA9 group, the weight change was similar to the group exposed solely to DSS, and the absence of any substantial decrease in DAI scores suggests that CA9 silencing effectively neutralized the therapeutic benefits of ATT-I (Figures 8A,B)
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