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Many young boys with this syndrome show undescended testicles (Cryptorchidism), and while a hormone treatment called human chorionic gonadotropin may be effective, most of them need a surgical procedure called orchiopexy. Hormone replacement therapy may be indicated for delayed puberty, and consultation with an endocrinologist is recommended at puberty

Off-label use may alter eating behaviors, emotional regulation, and mental health, potentially leading to increased anxiety, guilt, or disordered eating

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A vial that fails visual inspection has definitely lost potency and possibly sterility