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Using the arginine deiminase analog ADI-PEG-20 in hepatocellular carcinoma and glioblastoma has demonstrated antitumor activity in vitro and in xenograft models and demonstrated safety and efficacy in a phase I clinical trial

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Subsequently, the BMDMs were induced with interleukin-4 (IL-4, 40 ng/mL) or lipopolysaccharide (LPS, 100 ng/mL, Sigma-Aldrich, St

Insulin receptor substrate 2 acts through the AKT2/mTORC2 pathway (Nakamura et al., 2020

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