Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers
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(2023) highlight the importance of the estrobolome in regulating estrogen levels throughout a womans life, from menstruation to menopause
It was first isolated from human plasma, where it naturally occurs at concentrations of around 200 ng/mL at age 20, declining to approximately 80 ng/mL by age 60
However, when combined with retinol, it may cause irritation or sensitivity
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