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The $236 Billion Patent Cliff and What It Changes The context for all of this is a patent expiration wave that makes the 2012 patent cliff when blockbusters like Plavix, Lipitor, and Singulair lost exclusivity look modest

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The qPCR and western blot results showed that deprivation of R-loop did not influence the expression level of GADD45A, but lowered the expression of KCNQ5 protein level (Fig