studies on retatrutide Retatrutide, an experimental weight-loss drug, has not been approved by the FDA. But, doctors and nurse practitioners in clinics across the country are prescribing it anyway, a CBS News investigation Retatrutide Triple Agonist (GLP-1/GIP/GCG) |

2 How weight loss injections Work Weight loss injections help control the appetite and regulate blood glucose levels

The enthusiasm for potential therapeutic use of GLP-1 derives from studies demonstrating that unlike GIP, the glucose-lowering actions of GLP-1 are preserved in patients with type 2 diabetes

What are the biggest safety concerns with GLP1 use

In a 104-week extension (BMI 35 subgroup), mean weight loss reached -30.3% at 12 mg meaning the curve was still descending well past 80 weeks

Monitoring differences Patients on Toujeo need regular blood glucose monitoring, including fasting glucose checks and possibly continuous glucose monitoring

Unlike FDA-approved GLP-1 receptor agonists such as semaglutide or tirzepatide, these products are regulated as dietary supplements, not medications