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We recognise how important this moment is for the millions of people who live with excess weight or obesity and known heart disease, and we will continue to advance options that put their needs first

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Many semaglutide users need PPIs only during dose titration phases, then successfully step down to H2 blockers or lifestyle management alone once their body adjusts

PMID: 28648359

Pharmacological options are limited and used only within specialist services as part of a comprehensive weight management plan

This comparative approach has provided valuable insights into the biology of the IGF axis and its implications for health and disease