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The compound targets the substrate-binding site of NNMT and has been characterized in in-vitro enzyme-inhibition and cell-based studies

Cellular Aging and Longevity Oxidative stress is one of the primary drivers of the visible and internal signs of aging

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MOTS-c is also the better starting point for patients who want to support physical performance and recovery, because it acts as what researchers describe as an exercise mimetic, activating some of the same cellular pathways that exercise triggers

When taken outside the supervision of a physician or registered dietitian, she says supplements could actually lead to toxicity related to vitamin and mineral levels, some of which could present as dermatological symptoms

doi:10.3389/fendo.2023.1121387 PMID: 37051199