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Genetic variants in the GLP-1 receptor, differences in gut microbiome composition, and carnitine metabolism may all play a role
Here are the side effects doctors say they see most often: Nausea or stomach cramps: By far the most common complaints, nausea and stomach cramps usually improve as your body adjusts to the medication, according to the Mayo Clinic
31 Certain types of foods and beverages are commonly identified as triggers for worsening side effects: High-Fat, Greasy, or Fried Foods: These foods naturally take longer to digest
[8] It is also available as the fixed-dose combinations of sitagliptin/metformin (Janumet, Janumet XR) [8] and sitagliptin/simvastatin (Juvisync)
This delayed gastric emptying may theoretically alter the absorption rate of oral medications, including paracetamol, though this is not typically clinically significant for paracetamol specifically
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