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Nausea, vomiting, diarrhoea, stomach pain, constipation and headache are among the most common side effects

Importantly, recent in vivo studies have shown that genetic inhibition of FSP1 alone is sufficient to induce ferroptosis and suppress tumor growth, even in the absence of GPX4 inhibition 80,81

(The former study included a broad range of procedures with disparate complication rates, while the latter looked at only four procedures with similar complication rates

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However, many users find that staying on lower doses year-round (recomposition approach) produces similar or better long-term results with less dramatic physique fluctuations