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A major review in the International Journal of Molecular Sciences goes into depth on GHK Cus biological actions and why it has been used in skin and repair contexts, including discussions on collagen, glycosaminoglycans, and overall tissue regeneration signaling

Patients in their late 30s to early 50s who have begun noticing collagen loss but have not yet developed deep structural atrophy represent the sweet spot

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GHK-Cu is a naturally occurring copper peptide that modulates expression of over 4,000 human genes, including those involved in collagen synthesis, metalloproteinase regulation, and antioxidant defense

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