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Current protocols recommend treating patients with an initial dose of 150 mg/kg NAC, infused over a period of an hour, upon hospitalization, followed by decreasing amounts of NAC infused over the next 20 hours[1]

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The straight-up benefit of the once-monthly dose is you get 12 injections a year versus 52 a year, said Buse, who worked on the trial of Pfizers monthly shot

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STEP-1 and SURMOUNT-4, How Long Results Typically Last The STEP-1 trial extension provides a stark example of what happens after treatment stops