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The first studies evaluating the effects of GLP-1 and exendin-4 in neuronal cells demonstrated their ability to promote neurite outgrowth (a similar effect to that observed with the neurotrophic nerve growth factor) and to protect cultured neurons against glutamate-induced apoptosis [33]

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The medication targets your insulin levels, and as a result, you may end up feeling tired: If blood sugar drops too low, it can cause feelings of tiredness or lethargy, he says

Its table lists ACE inhibitors and ARBs as generally safe alongside a GLP-1, with the caveat that blood pressure should be monitored as weight comes off

PMCID: PMC6178160