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Moreover, the differentiation of circulating monocytes into autoinflammatory dendritic cells in the presence of IFN- promotes the activation and expansion of autoreactive lymphocytes, partially mediating an adaptive immune response (77)
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Fue identificado originalmente en el plasma humano, donde sus niveles disminuyen con la edad, un hallazgo que ha impulsado su estudio dentro de la investigacin del envejecimiento
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