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Vitamin B12 is used to treat pernicious anemia and vitamin B12 deficiency, as well as to determine vitamin B12 absorption in the Schilling test

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At a molecular level, glucose transporter 1 (GLUT1), the main glucose transporter across BBB, is densely expressed on the abluminal membrane of the BECs (Winkler et al., 2015)

COMPETING INTERESTS JST reports receiving an investigator-initiated grant, on behalf of the University of Pennsylvania, from Novo Nordisk and receiving consulting fees from Currax Pharmaceuticals, LLC

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