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Neuroinflammation, in which microglia and astrocytes take on an inflammatory phenotype and secrete toxic factors such as cytokines and nitric oxide, is another major component of neurodegenerative disease [57, 58]

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Sci Rep 6:21502 Graham SF et al (2016) Metabolic signatures of Huntingtons disease (HD): (1)H NMR analysis of the polar metabolome in post-mortem human brain

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