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Interestingly enough, oxidative stress did not affect the severity of depression

doi: 10.1002/1529-0131(200104)44:4 3.0.CO;2-0

For example, symptoms blamed on low energy may actually relate to anemia, thyroid disease, sleep problems, depression, infection, or cardiovascular disease

For BPC-157 specifically, the authors noted favorable tissue repair findings in animal models while explicitly flagging scarce human safety data

Native rhIGF-1 in IGF-1 Deficiency Chernausek et al., Journal of Clinical Endocrinology & Metabolism (2007) Chernausek and colleagues conducted the pivotal long-term clinical trial of recombinant human IGF-1 (mecasermin) in pediatric patients with severe primary IGF-1 deficiency the trial that supported FDA approval of Increlex for this rare growth-failure population