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3 Companies at the Forefront of the GLP-1 Pill Wars Though the first GLP-1 agonists date back more than 20 years, it's only in the last couple of years that they began to dominate the pharmaceutical space for their massive potential as weight loss drugs

There is no proven causal link in humans

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Upon entering systemic circulation, liraglutide demonstrates a notable affinity to bind to serum albumin (around 99%), leading to increased resistance to enzymatic breakdown by DPP-IV and NEP and a subsequent decrease in kidney-based elimination