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Low Se levels are currently considered to be one of the independent risk factors for thyroid diseases and Se supplement treatments for patients with low Se levels are thought to be generally beneficial for thyroid diseases

Sugrue, D

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580,581 Clinical progression of AD is defined first by massive synapse loss and subsequently by neuronal death, which ultimately results in profound brain atrophy and is clinically manifested by severe dementia

These include hydroxyl, superoxide and nitric oxide radicals, hydrogen peroxide, singlet oxygen, hypochlorous acid (HOCl), and peroxynitrite (Figure 1)