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GLP-1 AND DUAL AGONISTS In summary, the research progress of GLP-1 in lipid metabolism shows its potential in the treatment of metabolic disorders such as NAFLD, especially combined with its significant weight loss effect, making the application of GLP-1 in obese patients with NAFLD more worthy of in-depth exploration

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Endocrinology Research

Alteration of ATG genes have been found in diabetic mouse models, including the deletion of Atg5 and Atg7 in PTECs, which is associated with the accumulation of damaged mitochondria, tubular cell apoptosis and renal fibrosis (108)

As obesity rates climb, these molecules promise a scientific approach to stubborn weight