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In T1DM, SGLT-2 inhibitors are used cautiously due to the risk of diabetic ketoacidosis
Ian Strachan , a community pharmacist in Bury, Lancashire, who has run a weight loss service for about three years, points out that Saxenda (liraglutide), a product that is licensed for weight loss, can still be used, although there are intermittent supply challenges, he acknowledges The actions required of clinicians until supply issues have resolved are: GLP-1 RAs should only be prescribed for their licensed indication Avoid initiating people with type 2 diabetes on GLP-1 RAs for the duration of the GLP1-RA national shortage
Moreover, it has been investigated in research settings for its association with changes in body-composition markers, muscle-related signaling pathways, age-associated physiological indicators, sleep-related parameters, and biological processes involved in tissue recovery
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