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however, they are still not approved for use and available in the market

Given that more than half of total knee and hip arthroplasty patients meet criteria for obesity or morbid obesity, weight loss strategies, particularly pharmacologic approaches like GLP-1 receptor agonists, are becoming increasingly relevant in optimizing surgical outcomes and mitigating complications

Only articles published in English between 1980 and 2021 were included

59 Nevertheless, whether a GLP-1R agonist/GIPR antagonist can improve T2DM needs more evidences