4 GLP-1RAs (eg, tirzepatide, semaglutide, and liraglutide) are synthetic peptides that mimic endogenous GLP-1, and use of these therapies has expanded beyond their metabolic functions in type 2 diabetes and weight loss into other diseases due to their anti-inflammatory properties and their ability to modulate immune function
This creates an interesting divergence
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Evaluating Aprepitant single-dose plus granisetron and dexamethasone in children receiving highly emetogenic chemotherapy for the prevention of chemotherapy-induced nausea and vomiting: a triple-blinded randomized clinical trial
The combined effect can drive caloric intake quite low